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Name:
Metformin hydrochloride (Related Reference)
EINECS:
214-230-6
Molecular Formula:
C4H12ClN5
CAS Registry Number:
1115-70-4
Synonyms:
Diaformin; Dialon; Diformin; Diformin Retard; Dimefor; Fornidd; Geamet; Glucomin; Glucomine; Gluconil; Glucophage; Glucophage 850; Glucophage Forte; Glucophage Retard; Glucophage SR; Glufor; Gluformin; Glumeformin; Glumetza; Glumin; Glupermin; Glyceriphage; Glyciphage; Glycon; Metomin; Miformin; N,N-Dimethylbiguanide hydrochloride; N,N-Dimethylbiguanidinium chloride; N1,N1-Dimethylbiguanide hydrochloride; Orabet; Siamformet; Walaphage; Biguanide, 1,1-dimethyl-, monohydrochloride(8CI); Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI); 1,1-Dimethylbiguanide hydrochloride
Appearance:
crystalline solid
Molecular Weight:
165.62
Boiling Point:
224.1 °C at 760 mmHg
Melting Point:
223-226℃
Flash Point:
89.3 °C
Solubility:
Soluble in water, 95% alcohol. Practically insoluble in ether, chloroform.
Biological Activity:
Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines.
Usage:
An oral hypoglycemic agent
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